Japan
VOICE
  • TESTIMONIALS
  • PUBLICATIONS

PUBLICATIONS

  • Biochem Biophys Res Commun., 1997 May 8;234(1):269-74.
      • Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.
      Use of Alkaline water with low ORP to reduce Radical Damage

  • Biophys Chem. 2004, Jan 1;107(1):71-82.
      • The mechanism of the enhanced antioxidant effects against superoxide anion radicals of reduced water produced by electrolysis. Effect of Alkaline Water on Free Radicals

    Note : there are numerous publications on this topic. Many of the companies that sell instruments to make alkaline electrolysis water have opened up a new market in the USA. Kangen water for instance had $400M in sales last year. H4O can provide a more affordable solution for consumer who cannot

  • NATURE MEDICINE, 2007, Jun; 13(6):688-94. [Epub 2007 May 7.]
      • Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

  • NATURE MEDICINE, 2007, Jun; 13(6):673
      • The hydrogen highway to reperfusion therapy. ----Hydrogen gas debuts as a selective antioxidant with explosive potential as cytoprotective therapy for ischemiareperfusion injury and stroke.

  • BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, Sep 28; 361(3):670-4. [Epub 2007 Jul 25.]
      • Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress

  • NUTRITION RESEARCH, 2008, March 2008 (Vol. 28, Issue 3, Pages 137-143)
      • Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance

  • NEUROSCIENCE LETTERS, 2008 Aug 22; 441(2):167-72. [Epub 2008 May 24.]
      • Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model.

  • NEUROPHARMACOLOGY, 2008 Jun 18. [Epub ahead of print]
      • Consumption of Molecular Hydrogen Prevents the Stress-Induced Impairments in Hippocampus-Dependent Learning Tasks during Chronic Physical Restraint in Mice.

  • BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008 Aug 15;373(1):30-5. [Epub 2008 Jun 9]
      • Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury.

  • BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008 Oct 24;375(3):346-50. Epub 2008 Aug 14.
      • Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice.

  • NIPPON RONEN IGAKAKI ZASSHI 2008 Jul; 45(4):355-62. Japanese.
      • Hydrogen gas and hydrogen water act as a therapeutic and preventive antioxidant with a novel concept